TAQMAN MGB PROBE FOR DETECTING MATERNAL INHERITED MITOCHONDRIAL GENETIC DEAFNESS C1494T MUTATION AND ITS USAGE

摘要

Real-time quantitative MGB probe in detecting C1494T mutation matrilinear inheritance chondriosome deafness gene and its purposes. TaqMan mutant and the design of wild type MGB probes and pair of primers. C1494T mutated-genotypes in the chondriosome deafness gene of matrilinear inheritance are analyzed by real-time quantitative TaqMan MGB sonde methods. Therefore the chondriosome deafness of matrilinear inheritance can be diagnosis.