An anti-CCR5 antibody which comprises (i) two light chains, each light chain comprising the expression product of a plasmid designated pVK:HuPR0140-VK (ATCC Deposit Designation PTA-4097), and (ii) two heavy chains, each heavy chain comprising the expression product of either a plasmid designated pVgl:HuPR0140 HG2-VH (ATCC Deposit Designation PTA-4098) or a plasmid designated pVgl:HuPRO140 (mut B+D+I)-VH (ATCC Deposit Designation PTA-4099), or a fragment of such antibody, which binds to CCR5 on the surface of a human cell.
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机译:一种抗CCR5抗体,其包含(i)两条轻链,每条轻链包含称为pVK:HuPR0140-VK(ATCC保藏名称PTA-4097)的质粒的表达产物,和(ii)两条重链,每条重链包含称为pVgl:HuPR0140 HG2-VH(ATCC保藏编号PTA-4098)的质粒或名为pVgl:HuPRO140(mut B + D + I)-VH(ATCC保藏编号PTA-4099)的表达产物,或这种抗体的片段,与人细胞表面的CCR5结合。
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