METHOD FOR SIMULTANEOUS EXTRACTION AND ANALYSIS OF ENROFLOXACIN, DANOFLOXACIN AND CIPROFLOXACIN IN PIG BY USING SUPERCRITICAL FLUID EXTRACTION

摘要

A method for extracting enrofloxacin, danofloxacin and ciprofloxacin of fluoroquinolone-based antibiotics simultaneously from pork is provided to simplify extraction process by using supercritical fluid extraction. A method for extracting enrofloxacin, danofloxacin and ciprofloxacin of fluoroquinolone-based antibiotics simultaneously from pork comprises the step of extracting enrofloxacin, danofloxacin and ciprofloxacin from pork by using the supercritical carbon dioxide containing 10 % or more of an extraction aid at an extraction temperature of 40 deg.C or more and at an extraction pressure of 250 kg/cm^2 or more for 30 min or more by the supercritical fluid extraction.