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METHOD OF INHIBITION FOR TSC-22 MEDIATED APOPTOSIS BY FORTILIN

机译:酪蛋白抑制TSC-22介导的细胞凋亡的方法

摘要

The present invention relates to a pharmaceutical composition for inhibiting apoptosis containing a human fortilin gene or an expression protein thereof encoding the amino acid sequence of SEQ ID NO: 2. In another aspect, the present invention relates to a pharmaceutical composition for promoting apoptosis, which contains the expression of the human fortilin gene or an inhibitor of the expression protein as an active ingredient.;According to the present invention, it can be applied to various degenerative diseases such as dementia and Parkinson's disease using the pharmaceutical composition for inhibiting apoptosis containing the human fortilin gene or its expression protein, and the human fortilin ) Can be applied to diseases such as leukemia, cancer and psoriasis by using an expression of a gene or an inhibitor of the action of the expression protein.
机译:本发明涉及用于抑制细胞凋亡的药物组合物,其含有编码SEQ ID NO:2的氨基酸序列的人福尔马林基因或其表达蛋白。另一方面,本发明涉及用于促进细胞凋亡的药物组合物,其根据本发明,可以使用含有人fortilin基因的表达或表达蛋白的抑制剂作为活性成分,将其用于痴呆和帕金森氏病等各种变性疾病。人fortilin基因或其表达蛋白,以及人fortilin)可通过使用基因表达或表达蛋白的作用抑制剂而应用于诸如白血病,癌症和牛皮癣的疾病。

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