Method of Inhibition for TSC-22 mediated apoptosis by fortilin

摘要

The present invention relates to a pharmaceutical composition for inhibiting apoptosis containing the human motilin PO (fortilin) ​​gene expression or protein encoding an amino acid sequence of SEQ ID NO: 2. The invention also relates to a pharmaceutical composition for cell death promoting action containing an inhibitor of the expression or protein expression in the human motilin PO (fortilin) ​​gene as an active ingredient. ; According to the invention, the human PO motilin (fortilin) ​​by using a cell death suppressing pharmaceutical composition for the gene or containing the expressed protein can be applied to a variety of degenerative diseases such as dementia, Parkinson's disease, the human PO motilin (fortilin ) it can be expressed by using the action of the inhibitor or protein expression of a gene to be applied to diseases such as leukemia, cancer, and psoriasis.