Peptide mimetics, process for their preparation, pharmaceutical compositions containing them and their use as inhibitors of proteasomes and for the induction of apoptosis

摘要

The present invention relates to peptide-mimetic compounds, the synthesis and use thereof fort he inhibition of proteasomes and the induction of apoptosis in tumor cells. The present invention furthermore relates to pharmaceutical compositions comprising the compounds and the use of the compounds for a treatment of diseases, in particular cancer and neurodegenerative diseases.