Phosphine compounds, übergangsmetallkomlexe with the compounds as ligands are contained therein, and asymmetric synthesis of catalysts with these complex

摘要

PROBLEM TO BE SOLVED: To provide a new phosphine compound, and to provide an asymmetric synthesis catalyst which contains a transition metal phosphine complex containing the phosphine compound as a ligand and has excellent performances such as chemical selectivity, enantio selectivity, and catalyst activity as a catalyst for asymmetric synthesis reactions, especially asymmetric hydrogenation reaction.;SOLUTION: This phosphine compound represented by formula (1) [R¹ and R² are each H, a 1 to 10C alkyl, a 1 to 10C alkoxy, a 2 to 10C alkenyl, a di(1 to 5C alkyl)amino, a five to eight-membered ring alicyclic group, an aryl, an aralkyl, heterocyclic group, a tri-substituted silyl or a halogen; R³, R⁴, R⁵ and R⁶ are each H, a 1 to 5C alkyl, a 1 to 5C alkoxy, a di(1 to 5C alkyl)amino, a five to eight-membered cyclic amino or a halogen; R7 is a 1 to 5C alkyl, a 1 to 5C alkoxy, a di(1 to 5C alkyl)amino, a five to eight-membered cyclic amino or a halogen atom], and the asymmetric synthesis catalyst contains a transition metal phosphine complex containing the compound as a ligand.;COPYRIGHT: (C)2004,JPO