METHOD FOR PRODUCING OPTICALLY ACTIVE AROMATIC AMINO ACID AND OPTICALLY ACTIVE AROMATIC AMINO ACID AMIDE

摘要

PROBLEM TO BE SOLVED: To provide a biological production method of using a biocatalyst having advantageous stereoselectivity as a method for producing an optically active isomer, and for producing an optically active aromatic amino acid and an optically active amino acid amide, which is an antipode of the amino acid, in high reaction yield and with high stereoselectivity from an aromatic amino acid amide having poor water-solubility and, accordingly, being unable to increase the substrate concentration and being inadequate as a raw material for industrial production.;SOLUTION: An optically active aromatic amino acid and an optically active aromatic amino acid amide can be efficiently produced from hardly water-soluble aromatic amino acid amides by reacting them using cells of microorganisms belonging to the genus Mycoplana or Mycobacterium or its treated product in an aqueous solution having dissolved therein an organic solvent at a basicity of pH 7.5-10.5.;COPYRIGHT: (C)2010,JPO&INPIT