Under existing of the microbiology manufacturing method null reducing biochemical

摘要

PROBLEM TO BE SOLVED: To produce glycine from glycinonitrile by using a microorganism that can quantitatively form glycine and ammonia with high activity based on the dried cell bodies of the microorganism and per unit time without accompaniment of decomposition and discoloration during the cultivation, and can form glycine and ammonia quantitatively without a large volume of waste disposal of the cell bodies and culture medium and the addition or exhaustion of acids, alkalis of buffering solutions for adjusting the pH of the reaction mixture and can recover the glycine and the ammonia separately. ;SOLUTION: In the presence of a reductive biochemical compound, a microorganism or its treated product is allowed to act on glycinonitrile, preferably under the reaction condition in no need of addition of acid, alkali or buffer for adjusting the pH, or under the closed-system of the reaction condition or under reaction condition where the formed ammonia is exhausted out of the reaction system, as it is formed, a microorganism or its treated product is allowed to act on glycinonitrile to recover the formed glycine and the ammonia separately.;COPYRIGHT: (C)2001,JPO