Under existing of the microbiology production mannered null sulfurous acid

摘要

PROBLEM TO BE SOLVED: To provide a method for producing glycine from glycinonitrile using a microorganism, wherein the process is not accompanied by decomposition or discoloration, is efficient per dry cell mass per unit time, is not accompanied by the disposal of a large amount of cell or spent broth, is not accompanied by the addition or disposal of acid, alkali or buffer for adjusting pH of the reaction liquid, permits stoichiometrically producing glycine and ammonia, is not accompanied by any decomposition or consumption of these, and permits separately collecting these. ;SOLUTION: This method comprises such a process that glycinonitrile is subjected to a microorganism or product therefrom in the presence of a sulfite compound, preferably under a reaction condition that does not require adding acid, alkali or buffer for adjusting pH, in a closed system or system that permits simultaneous separation of formed ammonia outside the system, thus separately collecting glycine and ammonia.;COPYRIGHT: (C)2001,JPO