When growth breeding talent of the tumor cell (degree of malignancy) it distinguishes being newly born the target of tumor vessel inhibition medical therapy of application and cathepsin

摘要

PROBLEM TO BE SOLVED: To use cathepsin D or cathepsin E as a tumor marker.;SOLUTION: Growth proliferation and metastaticity (malignancy) of a tumor cell are determined by using cathepsin E as a tumor marker for tumors such as epidermoid cancer and measuring cathepsin E in serum. The cathepsin D or cathepsin E is introduced as a protein or a gene into the tumor cell. Thereby, enhancement of angiostatin production ability of cathepsin D and endostatin production ability of cathepsin E is induced and growth proliferation and metastasis of the tumor cell can be suppressed.;COPYRIGHT: (C)2005,JPO&NCIPI