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Transgenic non-human animal models of apoptosis-mediated conditions
Transgenic non-human animal models of apoptosis-mediated conditions
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机译:凋亡介导条件的转基因非人类动物模型
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摘要
A transgenic non-human animal whose genome comprises a stable integration of a transgene that encodes at least one Fas-ligand protein operably-linked to a tetracycline-inducible promoter includes cells that express the transgene and undergo apoptosis. The transgenic non-human animal can be used to screen for compounds that inhibit apoptosis and to identify cells that are capable of differentiating in vivo.
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