CRYSTALLINE PEPTIDE KETO-EPOXY INHIBITORS PROTEASIS AND SYNTHESIS OF KETO-EPOXID AMINO ACIDS

摘要

The present invention relates to crystalline peptide keto-epoxy compounds, to methods for their preparation and to related pharmaceutical compositions. The present invention also relates to methods for producing keto-epoxides of amino acids. Specifically, allyl ketones are stereoselectively converted to the desired keto epoxides.