首页> 外国专利> Phenyl- and pyridyl- tetrahydro-pyridines, method for preparing and pharmaceutical composition containing them and use thereof

Phenyl- and pyridyl- tetrahydro-pyridines, method for preparing and pharmaceutical composition containing them and use thereof

机译:苯基和吡啶基四氢吡啶,其制备方法和包含它们的药物组合物及其用途

摘要

It is described compounds of formula (I) wherein: X represents N or CH; R1 represents a hydrogen or halogen atom, or a CF3 group; R2 and R3 independently represent a hydrogen atom or a methyl group; n is 0 or 1; A represents a group of formula (a) or (b) wherein: R4 represents a hydrogen or halogen atom, a C1-C4 alkyl group, a CF3 group, an amino, mono(C1-C4)alkylamino, di(C1-C4)alkylamino; R5 represents a hydrogen or halogen atom, a (C1-C4)alkoxy group, a (C1-C4)alkyl group or a CF3 group; R6 represents a hydrogen atom, a (C1-C4)alkyl group or a (C1-C4)alkoxy group; and their salts or solvates, pharmaceutical compositions containing them, a method for preparing them and the synthesis intermediates in said method.
机译:描述了式(I)的化合物,其中:X代表N或CH; R1代表氢或卤素原子或CF3基团; R 2和R 3独立地表示氢原子或甲基。 n为0或1; A代表式(a)或(b)的基团,其中:R 4代表氢或卤素原子,C 1 -C 4烷基,CF 3基,氨基,单(C 1 -C 4)烷基氨基,二(C 1 -C 4) )烷基氨基; R5表示氢或卤素原子,(C1-C4)烷氧基,(C1-C4)烷基或CF3基; R 6表示氢原子,(C 1 -C 4)烷基或(C 1 -C 4)烷氧基。及其盐或溶剂化物,包含它们的药物组合物,其制备方法和所述方法中的合成中间体。

著录项

  • 公开/公告号SK287098B6

    专利类型

  • 公开/公告日2009-12-07

    原文格式PDF

  • 申请/专利权人 SANOFI - AVENTIS;

    申请/专利号SK20020000528

  • 申请日2000-10-19

  • 分类号C07D401;A43B7/12;A43B9/02;A61K;A61K31;A61K31/4427;A61K31/47;A61K31/4709;A61K31/4725;A61P;A61P1/04;A61P3/10;A61P7;A61P9;A61P9;A61P9/04;A61P9/10;A61P11/06;A61P13/12;A61P17;A61P17/06;A61P19/02;A61P19/08;A61P19/10;A61P25;A61P25/16;A61P25/28;A61P27/02;A61P29;A61P31/04;A61P31/10;A61P31/12;A61P31/18;A61P33/06;A61P35;A61P37;A61P37/06;A61P43;B29C45/14;B29C45/26;B29D35;B29D35/06;B29D35/12;B29D35/14;C07D;C07D215;C07D215/14;C07D217;C07D217/02;C07D401/06;C07D401/14;

  • 国家 SK

  • 入库时间 2022-08-21 18:45:02

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