thermostable antifungal peptide from a local secret of the filamentous fungus aspergillus clavatus strain.

摘要

the present invention relates to the screening and isolation of an antifungal peptide douu00e9u201a activitu00e9u201a thermostable. this peptide is secreted by a newly isolated aspergillus clavatus strain vr1.the invention also relates to the cultivation conditions for the determination of the factors affecting the production and the purification.the identification of the n-terminal and biochemical characterization, cloning and identification of the genomic structure of the gene encoding the activitu00e9u201a antifungal agent as well as the determination of its spectrum of action against plant and animal organisms.this new peptide named acafp, features such as interesting and original stability, stability during storage without the addition of additives, preservatives, stabilizers and / or its stability over a broad ph range.antifungal peptide has broad specificity for antagonists at low doses, primarily against the phytopathogenic fungus, fusarium oxysporum, an agent causing devastating damage to various crops.