METHOD FOR DELINEATING PERSONS AT HIGH RISK OF CHROMOSOMAL DISORDERS IN CHILDREN AND ADOLESCENTS WITH OSTEOARTHROSIS

摘要

A method for delineating the persons at high risk of chromosomal disorders in the children and the adolescents with osteoarthrosis provides for cytogenetic analysis of patterns and incidence of chromosomal disorders. For cytogenetic examination, methods of homogenous and differential C- and G-staining of the chromosomal preparations are used. The presence of 4-15 % of chromosomal disorders per 100 cells is indicative of high risk of chromosomal disorders.