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Host cell comprising a recombinant virus expressing an antigen and a recombinant virus expressing an immunostimulatory molecule

机译:宿主细胞,其包含表达抗原的重组病毒和表达免疫刺激分子的重组病毒

摘要

The present invention relates to a host cell infected using a composition of recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen to a disease causing agent and a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an immunostimulatory molecule(s) for the purpose of stimulating an immune response against the disease causing agent. Method of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms is provided using the composition.
机译:本发明涉及使用重组病毒组合物感染的宿主细胞,该组合物已在其基因组或其部分中掺入了编码致病因子抗原的基因,并且重组病毒已在其基因组或其部分中掺入了编码致病因子的基因。为了刺激针对疾病引起剂的免疫应答的免疫刺激分子。使用该组合物提供了治疗诸如癌症和由病原微生物引起的疾病的疾病的方法。

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