PROCEDURE FOR THE SYNTHESIS OF DEPROTECTED PENTASACCHARIDES FROM A PROTECTED PRECURSOR PENTASACCHARIDE

摘要

Procedure for the synthesis of deprotected pentasaccharides from a protected precursor pentasaccharide through a reaction procedure having five stages whereamong is included an N-sulphation of amino groups and a hydrogenolysis of benzyl groups. Through this procedure a drastic reduction is achieved in the total synthesis time in comparison with the process traditionally employed, together with increased reproducibility thereof, permitting the standardisation thereof.