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MARKER AND KIT FOR DIAGNOSING CHROMOSOMAL ABNORMALITY OF NEUROBLASTOMA THROUGH MICROARRAY

机译:通过微阵列诊断神经母细胞瘤染色体异常的标记物和试剂盒

摘要

PURPOSE: A kit and method for diagnosing chromosomal abnormality of novel neuroblastoma are provide to accurately measure the loss of chromosome through BAC(bacterial artificial chromosome) array.;CONSTITUTION: A CGH(comparative genomic hybridization) for diagnosing neuroblastoma comprises: a human second chromosome p25.3-p16.3 part which is able to confirm gain of chromosome by the increase of the number of DNA copies; a human seventh chromosome entire part which is able to confirm chromosome gain by increase of the number of DNA copies; a human 14th chromosome which is able to confirm chromosome deletion by reduction of the number of DNA copies and a human 22th chromosome q13.1-q13.2 part which is able to confirm chromosome deletion by reduction of the number of DNA copies.;COPYRIGHT KIPO 2010
机译:目的:提供一种用于诊断新型神经母细胞瘤的染色体异常的试剂盒和方法,以通过BAC(细菌人工染色体)阵列准确地测量染色体的丢失。;组成:用于诊断神经母细胞瘤的CGH(比较基因组杂交)包括:人类第二条染色体p25.3-p16.3部分,能够通过增加DNA拷贝数来确认染色体的获得;人类第七染色体的整个部分,能够通过增加DNA拷贝数来确认染色体的获得;能够通过减少DNA拷贝数来确认染色体缺失的人第14条染色体和能够通过减少DNA拷贝数来确认染色体缺失的人的第22染色体q13.1-q13.2部分。韩国知识产权局2010

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