MARKER FOR DIAGNOSING LYMPH NODE MICROMETASTASIS OF LUNG CANCER, KIT COMPRISING PRIMER FOR THE MARKER, MICROARRAY COMPRISING THE MARKER OR ANTIBODY AGAINST THE MARKER, AND METHOD FOR DIAGNOSING LYMPH NODE MICROMETASTASIS OF LUNG CANCER

摘要

A marker is provided to diagnose lymph node micrometastasis of lung cancer from a trace amount of biopsy at an early stage, thereby being utilized to an early diagnosis of the lung cancer and also used as a marker for detecting the micrometastasis from blood and bone marrow as well as lung. A marker for diagnosing lymph node micrometastasis of lung cancer comprises at least one polynucleotide. A kit for diagnosing lymph node micrometastasis of lung cancer comprises a sense and an anti-sense primers of the at least one of the polynucleotide described in the table 3. A microarray for diagnosing lymph node micrometastasis of lung cancer comprises the marker or an antibody recognizing a protein encoded by the marker. A method for diagnosing lymph node micrometastasis of lung cancer comprises the steps of: (a) obtaining a lung cancer sample from a lung cancer patient; (b) detecting expression or activity of the polynucleotide from the sample; and (c) diagnosing the lymph node micrometastasis of the lung cancer based on the detection result.