首页> 外国专利> DIFFERENTIATION PROMOTER AND/OR PROLIFERATION PROMOTER FOR ERYTHROCYTE STEM CELLS, USE OF METHIONINE FOR PREVENTING OR TREATING SENILE ANEMIA, AND COMPOSITIONS CONTAINING METHIONINE

DIFFERENTIATION PROMOTER AND/OR PROLIFERATION PROMOTER FOR ERYTHROCYTE STEM CELLS, USE OF METHIONINE FOR PREVENTING OR TREATING SENILE ANEMIA, AND COMPOSITIONS CONTAINING METHIONINE

机译:红细胞干细胞的分化促进剂和/或增殖促进剂,使用蛋氨酸预防或治疗老年性贫血以及含有蛋氨酸的成分

摘要

It is a first object to develop a remedy efficacious in preventing senile anemia which is frequently observed due to the aging. It is a second object to provide an antiaging drug, which has little side effect and is inexpensive and efficacious, in anticipation of the coming aging society. It is a third object to provide a remedy which is efficacious against anemia caused by myelosuppression, more particularly speaking, anemia occurring as the side effect of the administration of an anticancer agent. It has been clarified for the first time that a drug containing, as the active ingredient, methionine (Met) alone, an amino acid composition containing methionine (Met) together with one or more members selected from among glycine (Gly), serine (Ser) and threonine (Thr) or, furthermore, an amino acid mixture selected from (1) Ile, Trp, Thr, Val, His, Phe,Lys and Leu, (2) Ile, Thr, Val, His, Lys and Leu, (3) Trp, Thr, His, Phe and Lys, and (4) Ile, Trp, Thr, Val, Phe and Leu is capable of ameliorating and healing senile anemia. Thus, preventives for senile anemia, remedies for senile anemia and drugs for preventing cell aging can be provided.
机译:第一个目的是开发一种能有效预防由于衰老而经常观察到的老年性贫血的药物。第二个目的是提供一种抗衰老药物,其预期即将到来的老龄化社会具有很小的副作用并且廉价且有效。第三个目的是提供一种对由骨髓抑制引起的贫血有效的治疗方法,更具体地说,该贫血是作为抗癌剂给药的副作用而发生的。首次澄清的是,仅含有蛋氨酸(Met)作为有效成分的药物,其中含有蛋氨酸(Met)以及一种或多种选自甘氨酸(Gly),丝氨酸(Ser)的氨基酸组合物作为活性成分)和苏氨酸(Thr),或者进一步选自(1)Ile,Trp,Thr,Val,His,Phe,Lys和Leu的氨基酸混合物,(2)Ile,Thr,Val,His,Lys和Leu, (3)Trp,Thr,His,Phe和Lys,以及(4)Ile,Trp,Thr,Val,Phe和Leu能够改善和治愈老年性贫血。因此,可以提供用于老年性贫血的预防剂,用于老年性贫血的疗法以及用于防止细胞衰老的药物。

著录项

  • 公开/公告号KR20100098400A

    专利类型

  • 公开/公告日2010-09-06

    原文格式PDF

  • 申请/专利权人 MEIJI DAIRIES CORPORATION;

    申请/专利号KR20107013462

  • 发明设计人 ASAMI YUKIO;

    申请日2008-11-04

  • 分类号A61K31/198;A61K31/4172;C12N5/0789;A61P7;

  • 国家 KR

  • 入库时间 2022-08-21 18:31:59

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