首页> 外国专利> Erythrocyte stem cell differentiation promoter and / or proliferation promoter, and use of methionine for preventing or treating senile anemia and a composition containing methionine

Erythrocyte stem cell differentiation promoter and / or proliferation promoter, and use of methionine for preventing or treating senile anemia and a composition containing methionine

机译:红细胞干细胞分化促进剂和/或增殖促进剂,以及蛋氨酸在预防或治疗老年性贫血中的用途以及含有蛋氨酸的组合物

摘要

Since anemia is frequently observed with aging, the first task is to develop a therapeutic agent effective in preventing senile anemia. Furthermore, since aging will progress in the future, it is a second object to provide an inexpensive and effective anti-aging agent with low side effects. It is a third object to provide a therapeutic agent effective for anemia caused by bone marrow function suppression, specifically, anemia as a side effect of administration of an anticancer drug. The inventor of the present application includes a simple substance of methionine (Met), an amino acid composition composed of one or more selected from methionine (Met), glycine (Gly), serine (Ser), and threonine (Thr). Ile, Trp, Thr, Val, His, Phe, Lys and Leu, (2) Ile, Thr, Val, His, Lys and Leu, (3) Trp, Thr, His, Phe and Lys, (4) Ile, An agent containing an amino acid mixture selected from Trp, Thr, Val, Phe, and Leu as an active ingredient has been found for the first time to have the ability to improve and recover senile anemia. Agent and cell antiaging agent could be provided.
机译:由于经常在衰老中观察到贫血,因此首要任务是开发一种可有效预防老年性贫血的治疗剂。此外,由于老化将在未来进行,因此第二个目的是提供一种廉价且有效的,副作用少的抗衰老剂。第三个目的是提供对由骨髓功能抑制引起的贫血有效的治疗剂,特别是作为抗癌药给药的副作用的贫血。本申请的发明人包括蛋氨酸的简单物质(Met),由选自蛋氨酸(Met),甘氨酸(Gly),丝氨酸(Ser)和苏氨酸(Thr)中的一种或多种组成的氨基酸组合物。 Ile,Trp,Thr,Val,他的,Phe,Lys和Leu,(2)Ile,Thr,Val,His,Phe,Lys和Leu,(3)Trp,Thr,His,Phe和Lys,(4)Ile,An首次发现一种含有选自Trp,Thr,Val,Phe和Leu的氨基酸混合物作为有效成分的药物具有改善和恢复老年性贫血的能力。可以提供抗衰老剂和细胞抗衰老剂。

著录项

  • 公开/公告号JPWO2009066562A1

    专利类型

  • 公开/公告日2011-04-07

    原文格式PDF

  • 申请/专利权人 明治乳業株式会社;

    申请/专利号JP20090542517

  • 发明设计人 浅見 幸夫;

    申请日2008-11-04

  • 分类号A61K31/198;A61P43;A61K31/4172;A61K31/405;A61P7/06;A61P7;A23L1/305;

  • 国家 JP

  • 入库时间 2022-08-21 18:16:50

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