首页> 外国专利> BIOTRANSPLANT, METHOD FOR MAKING THEREOF AND METHOD OF TREATING DEGENERATIVE AND TRAUMATIC DISEASES OF MAXILLOFACIAL BONE TISSUE

BIOTRANSPLANT, METHOD FOR MAKING THEREOF AND METHOD OF TREATING DEGENERATIVE AND TRAUMATIC DISEASES OF MAXILLOFACIAL BONE TISSUE

机译:生物移植物,其制造方法和治疗颌面部骨组织变性和创伤性疾病的方法

摘要

FIELD: medicine.;SUBSTANCE: invention concerns medicine and represents a biotransplant for treating degenerative and traumatic diseases of bone tissue, characterised by that it contains autologous or donor multipotent mesenchymal stromal cells (MMSCs) of bone marrow or fatty tissue of adult donors which are distributed in a fibrinous clot in concentration 5-7 million cells per 1 ml, representing polymerised thrombocyte-enriched blood plasma of the patient, and a carrier based on collagen-mineral complex with identical composition as natural bone material, or biocompatible polymer.;EFFECT: invention provides creation of biological transplant for replacement of bone defects which is built-in in new-grown tissues, stimulates regeneration of tissues, while being a source of bone youth that leads to organotypic regeneration of bone tissue within defect and complete degradation of material in preset terms with reduction of by-effects.;6 cl, 3 ex
机译:技术领域本发明涉及医学并且代表一种用于治疗骨组织的变性和创伤性疾病的生物移植物,其特征在于其包含骨髓的自体或供体多能间充质基质细胞(MMSC)或成年供体的脂肪组织。分布在纤维状血凝块中,浓度为每1毫升5-7百万个细胞,代表患者的富含血小板的聚合血浆,以及基于胶原蛋白矿物质复合物的载体,其组成与天然骨材料相同,或具有生物相容性。 :本发明提供了用于替代骨缺损的生物移植物的创建,所述生物移植物内置在新近生长的组织中,刺激组织的再生,同时是骨骼年轻的来源,其导致缺损内的骨组织器官再生并完全降解材料以预设的方式减少副效应。; 6 cl,3 ex

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