METHOD FOR REGULATING PHOSPHORYLATION OF SR PROTEIN, AND ANTIVIRAL AGENT CONTAINING ACTIVITY REGULATOR OF SR PROTEIN AS ACTIVE INGREDIENT

摘要

PPROBLEM TO BE SOLVED: To provide an antiviral agent containing an SR activity regulator to regulate the activity of an SR protein as the active ingredient, and a compound to regulate the activity of the SR protein. PSOLUTION: The antiviral agent contains the SR activity regulator to regulate the activity of an SR protein, which is an expression vector for gene therapy having an HIV gene, an adenovirus gene and a vaccinia gene, and a new aniline derivative compound represented by the formula in the drawing, wherein RSP1/SPindicates a hydrogen atom, a 1-6C alkyl group or the like; RSP2/SPindicates a hydrogen atom, a 1-6C alkyl group or the like; RSP3/SPindicates a 1-6C alkyl group, a 6-10C aryl group, a nitrogen-containing heterocycle or the like; RSP4/SPindicates a hydrogen atom or a halogen atom; Q indicates -C(O)-, -C(S)- or the like; and W indicates a hydrogen atom, a 1-6C alkyl group, a 6-10C aryl group, a nitrogen-containing heterocycle or the like. PCOPYRIGHT: (C)2011,JPO&INPIT