首页> 外国专利> METHOD FOR PREDICTING MEDICINAL EFFECT OF HUMAN TYPE ANTI-TNFalpha ANTIBODY MEDICINE ON RHEUMATOID ARTHRITIS AND APPARATUS FOR PREDICTING MEDICINAL EFFECT

METHOD FOR PREDICTING MEDICINAL EFFECT OF HUMAN TYPE ANTI-TNFalpha ANTIBODY MEDICINE ON RHEUMATOID ARTHRITIS AND APPARATUS FOR PREDICTING MEDICINAL EFFECT

机译:预测人型抗TNFα抗体药物对类风湿关节炎的药物作用的方法及用于预测药物作用的装置

摘要

PPROBLEM TO BE SOLVED: To provide a method for predicting medicinal effects of a human type anti-TNF antibody medicine on rheumatoid arthritis in which effectiveness of human type anti-TNF antibody medicine to rheumatoid arthritis is predicted in high certainty and simply, activity of rheumatoid arthritis after administration of the medicine is predicted and useless side effects are avoided by administration of the medicine in a case in which the medicine is effective in more certainty, and to provide an apparatus for predicting medicinal effects. PSOLUTION: The method for predicting medicinal effects of human type anti-TNF antibody medicine on rheumatoid arthritis includes a step for measuring the content of at least any of ADAMTS4 and ADAMTS5 in a sample derived from a specimen and a step for evaluating whether a human type anti-TNF antibody medicine is effective to rheumatoid arthritis using the content of at least any of the ADAMTS4 and the ADAMTS5 as an index. PCOPYRIGHT: (C)2011,JPO&INPIT
机译:

要解决的问题:提供一种预测人型抗TNF抗体药物对类风湿性关节炎的药物作用的方法,其中高度肯定且简单地预测了人型抗TNF抗体药物对类风湿性关节炎的疗效,预测了给药后类风湿性关节炎的活性,并且在更确定地有效的情况下通过给药避免了无用的副作用,并提供了预测药物作用的装置。

解决方案:预测人型抗TNF抗体药物对类风湿关节炎的药物作用的方法包括以下步骤:测量标本中的样品中ADAMTS4和ADAMTS5中至少任何一种的含量,并评估是否人型抗TNF抗体药物以ADAMTS4和ADAMTS5中至少任何一种的含量为指标对类风湿性关节炎有效。

版权:(C)2011,日本特许厅&INPIT

著录项

  • 公开/公告号JP2011109929A

    专利类型

  • 公开/公告日2011-06-09

    原文格式PDF

  • 申请/专利权人 KAYTEE BIO CO & LTD;

    申请/专利号JP20090266539

  • 发明设计人 TSUSAKA NORIMASA;

    申请日2009-11-24

  • 分类号C12Q1/68;C12M1;C12M1/34;G01N33/50;C12N15/09;

  • 国家 JP

  • 入库时间 2022-08-21 18:22:18

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