In bioanalytical sensor applications, the device and method for studying transport of an agent across a bilayer membrane

摘要

A method for studying transport of an agent across the membrane, the invention is a surface of at least one a), the method comprising the steps of providing a surface with a bilayer structure tethered to the surface , resulting from the transport of agents across a step of contacting with one agent, and c) layer, in the detection volume at least to be analyzed, the method including the detection volume, two-layer structure wherein, b) a bilayer and the method comprising detecting a change in the refractive index. Further includes at least one sensor it is possible to detect double-layer structure of a single, a change in the refractive index and c) detection volume within the double layer, at least that is tethered one surface, b) a surface of at least a) surrounds the first volume of the detection volume, the structure is not enclosed by the bilayer structure, a volume of the second volume in the detection volume within the ratio of the volume of the second volume and the first , the device of greater than about 0.001 are provided.