FAST ASSIGNMENT OF ADEQUATE CHEMOTHERAPY WITH LATINUM BASED DRUGS FOR CANCER PATIENTS BASED ON THE IDENTIFICATION OF CONSTITUTIONAL BRCAL MUTATIONS

摘要

A new method to improve therapy outcome depending on a particular constitutional genotype have been disclosed. Subject of invention allows to synthesize DNA and identification of germline BRCA1 genetic abnormalities which are correlated with a significantly increased clinical response to chemotherapy based on platinum derived drugs in cancer patients.