首页>
外国专利>
Prodrugs activated by plasmin and their use in cancer chemotherapy
Prodrugs activated by plasmin and their use in cancer chemotherapy
展开▼
机译:纤溶酶激活的前药及其在癌症化疗中的应用
展开▼
页面导航
摘要
著录项
相似文献
摘要
The product of the invention is a modified form of a therapeutic agent and comprises a therapeutic agent, an oligopeptide having a plasmin peptide substrate of 2-4 amino acids and mono- or di-peptide linkage, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by plasmin. Also disclosed are methods of making and using the prodrug compounds.
展开▼