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uses of a monoclonal antibody, a genetically engineered or humanized fragment and / or antibody, a nucleotide sequence and a vector, product, and method for screening compounds

机译:单克隆抗体,基因工程或人源化片段和/或抗体,核苷酸序列以及载体,产物和化合物筛选方法的用途

摘要

USES OF A MONOCLONAL ANTIBODY, A FRAGMENT AND / OR GENETICALLY ENGINEED OR HUMANIZED ANTIBODY, A SEQUENCE OF NUCLEOTIDES AND A VECTOR, PRODUCT, AND METHOD FOR TRIALING COMPOUNDS Hepatocyte is described for the preparation of a medicament for the treatment of tumors and / or metastases and a diagnostic tool for detecting neoplastic cells as well as vectors comprising at least a portion of the nucleotide sequence encoding the anti-Met monoclonal antibody and / or at least one fragment thereof and at least one kinase inhibitor.
机译:单克隆抗体,片段和/或基因工程或人源化抗体的用途,核苷酸序列和矢量,产品以及化合物的试用方法描述了肝细胞用于制备用于治疗肿瘤和/或转移瘤的药物的方法本发明提供了用于检测赘生性细胞的诊断工具以及包含编码抗-Met单克隆抗体和/或其至少一个片段的核苷酸序列的至少一部分和至少一种激酶抑制剂的载体。

著录项

  • 公开/公告号BRPI0707480A2

    专利类型

  • 公开/公告日2011-05-03

    原文格式PDF

  • 申请/专利权人 METHERESIS TRANSLATIONAL RESEARCH S.A.;

    申请/专利号BR2007PI07480

  • 发明设计人 PAOLO MARIA COMOGLIO;

    申请日2007-02-05

  • 分类号C12N15/867;A61K39/395;A61K48;A61P35;A61P35/04;C07K14/71;C07K16/28;C12N15/13;G01N33/50;

  • 国家 BR

  • 入库时间 2022-08-21 18:07:10

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