Link ailadas molecules comprising a portion of binding to Antigen that binds to the Neo epitope that modulates complement Component C3b

摘要

The present compositions are described that Bind C3B Epitopes, and Methods of using the compositions. 1. - a Molecule comprising a portion of an isolated Link Link Antigen that binds with a Neo epitope c3b.2.- a Molecule of link isolated C3b, which includes a portion of the link that binds specifically with an Antigen epitope of C3B.Where the portion of link Antigen binds to an epitope of Human C3b within or Overlapping with one of the following: (a) gedtvqsltqg amino acids of the SEQ ID no: 1; (b) dediiaeenivsrsef amino acids of the SEQ ID no: 2; (c) irmnktvavrt amino acids of the SEQ ID no: 3; (d) sdovpdt amino acids ESET of SEQ ID no: 2; (e) vaqmted amino acids of the SEQ ID no: 5; (f) of the amino acids fvkrap SEQ ID: 6; (g) kdknrwedpgkqlyn amino acids of the SEQ ID no: 2; (H) amino acids ctryrgdqdatms SEQ ID no: 8; or (i) amino acids gfapdtddlkqlangv SEQ ID no: 9.3 - The C3b Molecule link of any of the preceding Claims, wherein the portion of link Antigen reacts cruzadamente With an Antigen from CB3 a non-human primate.