首页> 外国专利> PHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND USE THEREOF IN THE PREPARATION OF MEDICAMENTS FOR TREATING DISEASES MODULATED BY PPAR delta OR PPAR alpha AGONISTS

PHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND USE THEREOF IN THE PREPARATION OF MEDICAMENTS FOR TREATING DISEASES MODULATED BY PPAR delta OR PPAR alpha AGONISTS

机译:苯酚衍生物,其制备过程,组成其的药物组合物及其在制备用于治疗PPARδ或PPARα激动剂引起的疾病的药物中的用途

摘要

This invention relates to compounds of Formula (I) wherein one of R5, R6 and R7 is (Formula II), and X1, X2, Y1 to Y4, R1 to R13 and m and n are as defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.
机译:本发明涉及式(I)的化合物,其中R 5,R 6和R 7中的一个为(式II),并且X 1,X 2,Y 1至Y 4,R 1至R 13以及m和n如说明书中所定义。对映异构体及其药学上可接受的盐和/或酯本发明进一步涉及包含此类化合物的药物组合物,其制备方法以及其在治疗和/或预防由PPARδ和/或PPARα激动剂调节的疾病中的用途。

著录项

  • 公开/公告号IL175139B

    专利类型

  • 公开/公告日2011-10-31

    原文格式PDF

  • 申请/专利权人 F. HOFFMANN-LA ROCHE AG;

    申请/专利号IL175139

  • 发明设计人

    申请日2006-04-24

  • 分类号C07D213/30;C07D213/32;C07D213/38;C07D213/56;C07D213/82;C07D237/08;C07D239/26;C07D239/28;C07D241/12;

  • 国家 IL

  • 入库时间 2022-08-21 18:06:23

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