CHROMATIN REMODELING SUBSTANCES TO INCREASE THE EXPRESSION OF PDX-1 AND PROMOTE CELL DIFFERENTIATION

摘要

This invention relates to a method for inducing the differentiation of cells. In particular, this invention relates to methods that induce cells to differentiate into a pancreatic lineage, or into a pancreatic hormone-producing cell, or into a b-cell lineage. This invention also provides methods and compositions for utilizing such cells in the therapeutic treatment of diabetes.