ORAL PHARMACEUTICAL COMPOSITIONS OF ACID LABILE SUBSTANCES

摘要

The present invention relates to oral pharmaceutical compositions of acid labile substances, particularly proton pump inhibitors. These pharmaceutical compositions comprise one or more active units with each active unit comprising a core of a proton pump inhibitor, an intermediate layer of at least one lipophilic substance and an enteric layer. The invention also relates to a method for preparing one or more active units wherein the intermediate layer of lipophilic substances is applied to the core of a proton pump inhibitor in an aqueous emulsified form.