首页> 外国专利> NOVEL SUGAR CHAIN COMPOUND CONTAINING SIALYLLACTOSAMINE-TYPE OR SIALYL LEWIS X-TYPE SIALIC ACID AND FUCOSE

NOVEL SUGAR CHAIN COMPOUND CONTAINING SIALYLLACTOSAMINE-TYPE OR SIALYL LEWIS X-TYPE SIALIC ACID AND FUCOSE

机译:包含唾液酸乳糖胺型或唾液酸路易斯X型唾液酸和岩藻糖的新型糖链化合物

摘要

Provided is a novel and non-natural sialic acid-containing sugar chain compound, which has a binding activity to a viral particle and remains stable even in the presence of sialidase, obtained by using a reaction with the use of a glycosyltransferase having high substrate specificity and high reaction selectivity.A compound having a sugar chain structure represented by general formula (1): Siaα2-3(Siaα2-6)Galβ1-4(Fucα1-3)GlcNAc (1), or a salt thereof.
机译:本发明提供通过与具有高底物特异性的糖基转移酶反应而得到的新颖的非天然的含唾液酸的糖链化合物,其与病毒颗粒具有结合活性,即使在存在唾液酸酶的情况下也保持稳定。和高反应选择性。具有通式(1)表示的糖链结构的化合物:Siaα2-3(Siaα2-6)Galβ1-4(Fucα1-3)GlcNAc(1)。

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