INTESTINAL MUCOSA-INHERENT MYELOID CELLS INHIBITING T CELL ACTIVATION AND UTILIZATION OF SAME

摘要

It was discovered that myeloid cells, which occurs in the lamina propria of healthy animals and are highly positive to Gr-1, positive to CD11b and positive to CD11c, can induce T cell apoptosis and, in its turn, inhibit T cell activation. These myeloid cells are highly useful as the active ingredient of an immunomodulator that is applicable to the prevention or treatment of inflammatory bowel disease and so on.