VITAMIN D DETECTION BY MASS SPECTROMETRY WITH LASER DIODE THERMAL DESORPTION

摘要

Methods are provided for determining the amount of one or more vitamin D metabolites in a sample using mass spectrometry. The methods generally comprise volatilizing a sample by heating with a laser, ionizing one or more vitamin D metabolites in the volatilized sample, and detecting the amount of one or more ions by mass spectrometry. The methods may be used to detect two or more vitamin D metabolites in a single assay.