Nematoden als Modellorganismen zur Untersuchung neurodegenerativer Erkrankungen und insbesonder der parkinsonschen Erkrankung, Verwendung und Verfahren

摘要

the present invention relates to nematodes as model organisms for the study of neurodegenerative diseases and, in particular, parkinson's disease, uses and procedure for the detection of substances and genes in the treatment of such diseases can be used and the identification of a nematodengens from c.elegans, the parkinson's disease associated human parkingen homolog.;the present invention relates in particular to the nematodes, which involve aberrant or lack of expression of at least one gene that is associated with parkinson 's disease, preferably a parkingens and / or a d - synucleingens).the erfindungsgemu00e4u00dfen organisms may, in particular, for identification and characterization of drugs for the treatment of such diseases.