Recombinant scFV Lym-1 antibody comprising lysine residues, gene encoding the same, host cell expressing the gene, and composition and method of treating or diagonising a cancer comprising the antibody

摘要

The invention scFv (single chain variable fragment) Lym-1 antibody, a histidine tag (His Tag) and four lysine amino acid is N-terminal in the C-terminus to the sequence as linked amino acid sequence to contain human leukocyte antigen group Apoptosis receptor (HLA-DR) to specifically scFv Lym-1 recombinant antibody binding, gene encoding him, the recombinant expression vector containing the gene, a host cell transformed with the recombinant vector, a method of manufacturing the above antibody, the antibody It provides a treatment of cancer or a diagnostic composition and method comprising a. ; scFV Lym-1 antibody, a histidine tag, the expression vector