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METHOD FOR PRODUCTION OF REMEDY WITH ANTINEOPLASTIC ACTIVITY AND REMEDY WITH ANTINEOPLASTIC ACTIVITY

机译:产生具有抗肿瘤活性的药物的方法和具有抗肿瘤活性的药物

摘要

FIELD: food industry.;SUBSTANCE: method involves preparation of inoculation mycelium of basidiomycetes, preparation of productive nutrient medium and inoculation of the productive nutrient medium, containing carbohydrate and nitrogen source and mineral salts, with the prepared inoculation mycelium. Basidiomycetes cultivation with subsequent production of an immersion culture. The inoculation mycelium preparation is performed in a sterile nutrient medium containing glucose, soya flour, potassium dihydrogen phosphate, magnesium sulphate and arachidonic acid. The inoculation mycelium growing is performed at a temperature of 22-29°C during 2-6 days under aeration conditions with its subsequent homogenisation.;EFFECT: antineoplastic remedy produced from the basidiomycetes immersion culture is effective and the cultivation process duration is reduced from 2-3 weeks to one week; mycelium yield increases.;23 cl, 6 tbl, 12 ex
机译:领域:食品工业;物质:该方法涉及制备担子菌的接种菌丝体,制备生产性营养培养基以及用所制备的接种菌丝体接种包含碳水化合物,氮源和无机盐的生产性营养培养基。担子菌培养,随后产生沉浸培养物。接种菌丝体的制备是在含有葡萄糖,大豆粉,磷酸二氢钾,硫酸镁和花生四烯酸的无菌营养培养基中进行的。接种菌丝体在曝气条件下于22-29°C的温度下进行2-6天的生长,然后进行均质化;效果:从担子菌浸没培养产生的抗肿瘤药物有效,培养过程的持续时间从2减少-3周至1周;菌丝体产量增加。; 23 cl,6 tbl,12 ex

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