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METHOD OF TREATING SQUAMOUS CELL CANCER OF ANAL CANAL

机译:治疗肛管鳞状细胞癌的方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, oncology, and can be used for treating squamous cell cancer of anal canal. That is ensured by two-stage therapy every 2-3 weeks. The I stage involves beam therapy on the area of small pelvis: a primary tumour, pararectal, pelvic, inguinal lymph nodes from both sides. A single basic dose is 2 Gy for 20 sessions to total basic doses 44 Gy. Starting with the 9th sessions of beam therapy, the radiation fraction is preceded with 5 sessions of local electromagnetic hyperthermia. On the 2nd and 4th days of local electromagnetic hyperthermia sessions, metronidazole as an ingredient of a composite mixture is introduced through rectum with exposition 5 hours before radiation. On the days of the introduction of metronidazole, local electromagnetic hyperthermia follows the radiation fraction with single basic dose 4 Gy.;EFFECT: method allows avoiding a surgery, namely combined abdominoperineal resection, increasing recurrence-free survival rate and improving quality of life of the patients.;2 cl, 1 tbl, 2 ex
机译:领域:药物:本发明是指药物,肿瘤学,并且可以用于治疗肛管鳞状细胞癌。每2-3周进行两阶段治疗可以确保这一点。 I期涉及小骨盆区域的束治疗:两侧的原发性肿瘤,直肠直肠,骨盆,腹股沟腹股沟淋巴结。单次基本剂量为2 Gy(持续20个疗程),而总基本剂量为44 Gy。从第9疗程束治疗开始,在放射分数之前进行5疗程局部电磁热疗。在局部电磁热疗的第2天和第4天,将甲硝唑作为复合混合物的成分通过直肠暴露,并在辐射前5小时进行暴露。在引入甲硝唑的日子里,局部电磁热疗遵循单一基本剂量4 Gy的辐射分数。效果:该方法可避免手术,即联合腹部手术切除,提高无复发生存率并改善患者的生活质量。患者。; 2 cl,1 tbl,2前

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