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METHOD OF TREATING SQUAMOUS CELL CANCER OF ANAL CANAL

机译:治疗肛管鳞状细胞癌的方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, specifically to oncology, and can be used in treating squamous cell cancer of anal canal. Method involves exposure of tumour to radiation teletherapy in a single basic dose 2 Gy, total radiation dose 50-56 Gy for 35-40 days, 5 times a week combined with chemotherapy mitomycin C in dosage of 10 mg/m2 on first day of treatment intravenously, with capecitabine. Capecitabine is used in dose of 650 mg/m2 2 times a day on days of radiation therapy orally, and paclitaxel is added in dose of 45 mg/m2 1 time a week for 5 weeks intravenously.;EFFECT: using invention enables complete tumour regression in 91 7/10 % patients with squamous cell cancer of anal canal with predominance of common T3-T4 steps and/or involvement of regional lymph nodes without application of surgical treatment.;1 cl, 2 ex
机译:技术领域本发明涉及医学,特别是涉及肿瘤学,可用于治疗肛管鳞状细胞癌。该方法涉及将肿瘤以单一基本剂量2 Gy,总放射剂量50-56 Gy暴露于放射远距照射下35-40天,每周5次,并与化疗丝裂霉素C联合使用,剂量为10 mg / m 2 <在第一天静脉注射卡培他滨。在口服放射治疗的日子中,每天口服卡培他滨的剂量为650 mg / m 2 2次,而紫杉醇的剂量为45 mg / m 2 1次效果:使用本发明可以使91 7/10%的肛管鳞状细胞癌患者完全消退肿瘤,其主要表现为T3-T4常见步骤和/或局部淋巴结受累,而无需进行手术处理。; 1 cl,2 ex

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