USE OF RITONAVIR (ABT-538) FOR IMPROVING PHARMACOKINETIC OF DRUG METABOLIZED BY CYTOCHROME P450 IN METHOD OF TREATING AIDS

摘要

PROBLEM TO BE SOLVED: To provide a method for improving pharmacokinetics of drugs which are metabolized by cytochrome P450 monooxygenases.SOLUTION: The method comprises administering a combination of: the drugs which are metabolized by cytochrome P450 monooxygenases or pharmaceutically acceptable salts thereof; and ritonavir or a pharmaceutically acceptable salt thereof.