Two-photon dye for real-time monitoring of free zinc ion in cytoplasm, method for producing the same, and real-time monitoring method for free zinc ion in cytoplasm using the same

摘要

A two-photon probe for real-time monitoring of intracellular free zinc ions is provided. The two-photon probe is represented by Formula 1: wherein R is H or OCH 3 . The two-photon probe has high selectivity for Zn 2+ and enables very effective and long-term monitoring of intracellular free Zn 2+ present in the deep tissue. Further provided are a method for preparing the two-photon probe and a method for real-time monitoring of intracellular free zinc ions using the two-photon probe.