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METHOD FOR ANALYZING NUCLEIC ACID MUTATION USING ARRAY COMPARATIVE GENOMIC HYBRIDIZATION TECHNIQUE

机译:阵列比较基因组杂交技术分析核酸突变的方法

摘要

There is provided a method for analyzing nucleic acid mutation using an array comparative genomic hybridization technique, which reduces the false positive and the false negative and improves the reliability of the analysis results. A method for analyzing nucleic acid mutation using array comparative genomic hybridization technique comprising: [(a) a step of bringing a plurality of labeled sample nucleic acids one by one into contact with the plural same probe nucleic acid sets], [(b) a step of obtaining label intensities], [(c) a step of determining whether each piece of comparison values falls within a prescribed numerical value range or not], and [(d) a step of comparing whether the number of the comparison values exceeds a prescribed number or not and, in the case of exceeding the prescribed number, judging the spot positive].
机译:提供了一种使用阵列比较基因组杂交技术分析核酸突变的方法,该方法减少了假阳性和假阴性并提高了分析结果的可靠性。一种使用阵列比较基因组杂交技术分析核酸突变的方法,包括:[(a)使多个标记的样品核酸一个接一个地与多个相同的探针核酸组接触的步骤],[(b)a [获得标签强度的步骤],[(c)确定每个比较值是否落在规定的数值范围内的步骤],[[d]比较比较值的数量是否超过是否达到规定的数量,如果超过规定的数量,则判定为阳性。

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