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Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient
Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient
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机译:用于干粉吸入器的药物制剂,包含低剂量强度的活性成分
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摘要
The invention provides a formulation to be administered as dry powder for inhalation suitable for efficacious delivery of low-dosage strength active ingredients to the low respiratory tract of patient. In particular, the invention provides a formulation comprising microparticles constituted of microparticles of a low-dosage strength active ingredient and microparticles of an excipient wherein the MMD of the microparticles is comprised between 2 and 15 micron, at least 10% of the microparticles has a mass diameter (MD) higher than 0.5 micron, and the process of preparation thereof.
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