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METHOD FOR STEREOSELECTIVE SYNTHESIS OF BICYCLIC HETEROCYCLIC COMPOUNDS.

机译:立体选择合成双环杂环化合物的方法。

摘要

The present invention relates to a method for stereoselectively producing compounds of the formulas (1A) and (1B) and the salts thereof, particularly the physiologically compatible salts thereof having inorganic or organic acids and bases, comprising valuable pharmacological properties, particularly an inhibiting effect on signal transduction mediated by tyrosine kinases, the use thereof for treating diseases, particularly tumor diseases and benign prostata hyperplasia (BPH), and diseases of the lungs and airway.
机译:本发明涉及立体选择性地制备式(1A)和(1B)的化合物及其盐,特别是具有无机或有机酸和碱的其生理相容性盐的方法,该方法包括有价值的药理性质,特别是对H2O3的抑制作用。酪氨酸激酶介导的信号转导,其在治疗疾病,特别是肿瘤疾病和良性前列腺增生(BPH)以及肺和气道疾病中的用途。

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