STUDY ON THE SYNTHESIS OF BRASSINOLIDE AND RELATED COMPOUNDS 15.FORMAL SYNTHESIS OF BRASSINOLIDE VIA STEREOSELECTIVE SULFENATE-SULFOXIDE TRANSFORMATION

摘要

A formal synthesis of the natural growth promoting steroidbrassinolide is described,which involves construction of side chainby 1,3-sulfoxide-hydroxyl transposition with methylation from(24S)-22-E-24-sulfoxide 6 and(24R)-22-E-24-sulfoxide 9,respectively to(22S)-23-E-24-methyl compound 4.