Use of compound n-phenyl-N '- (3-methyl-2-butenyl) thiourea to prepare medicaments for the treatment of hepatic encephalopathy.

摘要

Use-N N-phenyl compound - (3-methyl-2-butenyl) thiourea to prepare medicaments for the treatment of hepatic encephalopathy # The present invention relates to N-phenyl pharmaceutical composition comprising the compound. -N - (3-methyl-2-butenyl) thiourea and the use of N-phenyl-N compound - (3-methyl-2-butenyl) thiourea and said pharmaceutical composition in the manufacture of medicaments for the treatment of diseases with hyperammonemia, such as, but not limited thereto, generally hepatic encephalopathy or hepatic encephalopathy caused by cirrhosis in particular. This compound is capable of partially inhibiting the enzymatic activity of intestinal glutaminase activated phosphate (GAP), causing a reduction in ammonia production.