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Fusion protein syndrome virus and porcine respiratory player as a vaccine against PRRS
Fusion protein syndrome virus and porcine respiratory player as a vaccine against PRRS
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机译:融合蛋白综合症病毒和猪呼吸道疾病疫苗作为抗PRRS疫苗
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摘要
Fusion protein of the virus reproductive syndrome and porcine respiratory (PRRSV), comprising: a) a peptide of Pseudomonas exotoxin (PE) comprising a binding domain and detranslocación N-terminal domain, located at the end the fusion protein, b) a fusion peptide of ORF6-5 February 26 (SEQ ID NO: 11) and ORF5-31-63 (SEQ ID NO: 10) of cepaamericana PRRSV or fusion peptide ORF6- M1-I28 (SEQ ID NO: 12) and F31 ORF5-A64 (SEQ IDNO: 13) of European PRRSV strain; c) a carboxyl-terminal domain comprising the amino acid sequence KDEL-KDEL-KDELubicada at the C-terminus of the fusion protein, in which the capital letters "KDEL" amino acid codes represent a single letter.
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机译:病毒繁殖综合症与猪呼吸道融合蛋白(PRRSV),包括:a)假单胞菌外毒素(PE)的肽,其位于结合蛋白的末端,包含结合结构域和去转位N端结构域,b)融合肽2月26日ORF6-5-5(SEQ ID NO:11)和ORF5-31-63(SEQ ID NO:10)的特征欧洲PRRSV毒株的SEQ ID NO:13); c)在融合蛋白的C-末端包含氨基酸序列KDEL-KDEL-KDELubicada的羧基末端结构域,其中大写字母“ KDEL”氨基酸代码表示单个字母。
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