1-ALKYL-5-ARYL-3-ARYLAMINO-1H-1,2,4-TRIAZOLES AS POSITIVE ALLOSTERIC MODULATORS OF THE ALPHA 7 RECEPTOR

摘要

The present invention relates to 3-aniIine-5-aryl triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I). The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.